Genetics Test Update

Due to the Snow Day on Wed 2/27, the Genetics Test has been moved to Fri 3/1.  Prepare yourself by learning about 2 single gene genetic disorders, review how to set up a dihybrid Punnett Grid and complete it, review how to do a chi-squared test, calculating expected values, plugging into the equation, and interpreting the results.  Much of this information is in 10.2 and can also be found in the Genetics Notes on-line.  We will start Sections 2.6 and 2.7 right away after the test because we will have to cover the next unit before Spring Break!

Information about the Genetics Test and Assignments for Monday 2/25

On Monday 2/25, we will be reviewing for the Genetics Test (including Kahoot!), checking off some assignments, and going over the genetics problems.  This is what I will check off:

1.  DBQ's from pp. 452-454.  On pp. 452-453, pretty much ignore the directions and do 2 things with the 2 sets of data that you get.  1)  Calculate the recombinant frequencies using the smaller numbers for recombinants and 2) Calculate the expected results if these genes were not linked.  For the DBQ on p 454, you can do it as instructed.  The contingency table is basically a chart showing the observed and expected numbers for all 4 phenotypes.
2. For the Card Lab:  1)  Your observed results for all 3 phenotypes  2)  Your expected results for the 3 phenotypes, showing work   3)  the Chi-squared calculation, showing work    4)  the critical value (see chart on p. 454)  and 5)  Your interpretation of the result

This is what will be on the Genetics Test on Wednesday 2/27.  There is a bit more on the Review Sheet in the documents section of this blog:

For the Test, Know how to:

1. Draw Punnett Grids to predict genotypes and phenotypes of monohybrid and dihybrid crosses
2. Apply Laws of Probability to predict genotypes and phenotypes of crosses
3. Analyze a Pedigree to determine genotypes of a family and to determine whether a family trait is dominant, recessive, autosomal, or X-linked
4. Do problems involving the ABO blood groups in humans
5. Make predictions involving sex-linked traits
6. Calculate chi-squared results and determine whether hypothesis should be accepted (you will be given equation and chart for determining significance)
7. Identify which of the offspring are recombinants in a dihybrid cross involving linked genes and calculate recombinant frequencies
8. Explain the genetic causes, symptoms, and potential treatments and interesting facts for 2 single-gene disorders.  Some examples include sickle cell anemia, Huntington’s disorder, cystic fibrosis, maple syrup urine disease, galactosemia, phenylketonuria (PKU), and many more!

Mid-February

• Tuesday 2/12:  Questions on Harder Genetics Problems so far?  Pedigrees.  Sex-linked Disorders.  Hand out Pedigree worksheet and complete it.  Continue working on Harder Genetics Problems, now both sides.  Problems should be done on separate paper, showing work, and are due Tues 2/19.
• Thurs 2/14:  Genetic mutation and disorders.  Polygenic inheritance.  Research a genetic disorder.  Work on genetics problems.  Get Pedigree worksheet checked off.  Read 10.2.
• Tues 2/19:  Turn in genetics problems.  Linked genes and gene mapping.  DBQ's.  
• Thurs 2/21:  Chi-squared test.  Card simulation for chi-squared test.
• Mon 2/25:  Review for Genetics Test.
• Wed 2/27:  Genetics Test.  Start DNA Transcription.  Read 2.7 and 7.1.