3/18-3/22

SPARK lecture this Monday 3/18 on engineering.  Replication/Transcription/Translation/Enzyme Test on Thursday.  Turn Enzyme Inquiry Lab in before Spring Break (or get it to me via e-mail by Sun 3/24).  Please also turn in a copy through turnitin.com.

• Mon 3/18:  Notes on Enzymes.  Questions on Enzyme Lab?  Turn in Enzymes as Agents of Control if not already.  Graph and short conclusion required.
• Tues 3/19:  Jeopardy Review for Replication/Transcription/Translation/Enzyme Test.  Work on Review Sheet to be turned in BEFORE the test on Thursday.
• Thurs 3/21:  Turn in test review.  Take Test.  Start biotechnology.  Turn in Enzyme Lab.  Hand out Seed Germination Lab.  It is not going to be due until the 2nd week of May, but many of you might want to work on this over Spring Break if you are around since it has to be done at home and requires  vigilance over a number of days.

Enzyme Lab: Turn in before Spring Break or by Sun, 3/24

For this lab, please turn in a hard copy and submit via turnitin.com.  The class ID:  6240228 and password:  enzyme.  I will put up some instructions for signing in to turnitin.com.

What do you need for a full lab write-up? 
1.  Focused Question
2.  Background
3.  Variables (identify the 3 types).  Sometimes students discuss how they controlled the variables here.
4.  Materials
5.  Procedure, remember the details!!  Include specific amounts, tools used, how you controlled variables.  Include what you are going to do to the data.
6.  Data table, has to have uncertainty and all of the usual things
7.  Data processing:  sample calculations, graphs, statistical tests where relevant
8.  Conclusion
9.  Evaluation

For more details on all of these, look at your IB Biology Survival Manual.

What should you know for the quiz on Thursday?

1.  Describe the process of replication using the following terms:  replication fork, leading strand, lagging strand, Okazaki fragments, 5’ to 3’ synthesis

2.    Names and functions of the 6 enzymes:  helicase, RNA primase, DNA polymerase III, DNA polymerase I, ligase, and RNA polymerase

3.   3 differences between DNA and RNA.

4.    Know the 3 stages of transcription and be able to describe them BRIEFLY

5.    Be able to describe the 3 modifications to RNA before it leaves the nucleus

3/4-3/14

SPARK Lecture this Monday (3/4)  on Computer Science.  Room 169 at 3:30 pm.

• Mon 3/4:  Mutations in your name worksheet.  Use the genetic code to write your name and then investigate how it changes as it goes through various "mutations".
• Tues 3/5:  Translation:  going from RNA to protein.  Overview of the whole process.   Start Enzyme Worksheet.
• Thurs 3/7:  Short Quiz on Replication and Transcription.  Finish Enzyme Worksheet while each group does Transcription/Translation Simulation.  Introduce Enzyme Inquiry Lab.
• Mon 3/11:  Try 3 different methods of measuring enzyme activity.
• Tues 3/12:  "Messing Around Day" for Enzyme Inquiry Lab.  Do pre-write for Enzyme Inquiry Lab.  Hand out Review Sheet for test on replication/transcription/translation/enzymes.
• Thurs 3/14:  Take data for Enzyme Inquiry Lab.  Full lab write-up due by Thursday 3/21 (extended to Sun 3/24).  Replication/Transcription/Translation/Enzyme Test next Thursday 3/21.  

2/25-2/29

• Mon 2/25:  Molecules of chromosomes.  Double helix discovery.  Overview of replication.  Finish Replication worksheet and turn in.  Read Chapter 16.
• Tues 2/26:  Turn in Replication Worksheet if not already.  On-line simulation of replication.  In table groups, simulate DNA replication using paper models.  Start transcription.  
• Thurs 2/28:  Transcription to translation.   Dictionary of the genetic code.  Mutations in your name worksheet.   Read 17.1 

Answers to Genetics Review

Here are the answers to the review sheet.  You need to turn in the Review Sheet, with work shown, before the test on Thursday.

1.  a)  PPLlx PPLl, PPLl x ppLl, PPLl x PpLl and other options
b)  ppLl x ppLl
c)  PPLL x ppll, PPLL x PPLL, PPLL x PpLl and many other options
d)  PpLl x Ppll
f)  PpLl x PpLl

2.  a)  1/256   b)  1/16   c)  1/64    d)  1/128
3.  1/9
4.  3 purple, 5 white
5.  9 A+, 3 A-, 3 O+, 1 O-
6.  a)  because the genes were linked on the same chromosome and did not sort independently
b)  0.6 %

The Genetics Test is going to be on Thursday, 2/21.  On Tuesday, you will be taking an OAKS test and starting DNA Replication.  Remember to study the 6 genetics disorders, know how to do a dihybrid Punnett Square, and know how to do a Chi-squared test and interpret it.  See Review Sheet for other questions.

A New Semester!!

• Mon 2/4:  Final Exams Back and Recollect.  Probability Laws and Genetics.  Hand out Genetics Problem Set due next Monday 2/11.  Do answers on a separate sheet and show work.  Read Chapter 14.
• Tues 2/5:  Chi-Squared test and Genetics.  Using playing cards to simulate a cross producing flowers. Complete the Card Simulation hand-out and turn in today or Thursday.  
• Thurs 2/7:  X-linked traits.  Pedigrees.  Pedigree worksheet due next Wednesday.  Genetics Problems due on Monday.  Watch "Ghost in Your Genes" video and turn in video notes.
• Mon 2/11:  Turn in genetics problem-set.  Questions on Pedigrees?  Computer research on genetics disorders.
• Wed 2/13:  Check off pedigree worksheet and go over.  Linked genes and gene mapping.  Hand out Genetics Review Sheet and work on problems.
• Fri 2/15:  Short classes today.  Go over problems on Genetics Review Sheet.  Genetics Test next Tuesday, 2/19. Thursday, 2/21.